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Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors.
By NATURE MEDICINE Effective cancer immunotherapy requires the release of a broad spectrum of tumor antigens in the context of potent immune activation. We show here that a cDNA library of normal tissue, expressed from a highly immunogenic viral platform, cures established tumors of the same histological type from which the cDNA library was derived. […]
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Information about the situation of the Japanese nuclear reactors in Fukushima
For information about the situation of the Japanese nuclear reactors in Fukushima Central – Japan, visit the link below (IAEA): http://www.iaea.org/press/
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Nanodiamonds in cancer treatment
By ISTO É FTP U.S. researchers said on Wednesday (09/03) the discovery of a way to attack tumors in advanced stages of breast cancer and liver, using a potent chemotherapy drug combined with tiny carbon particles known as nanodiamonds. The technique was tested in mice and showed that nanodiamonds help the doxorubicin to penetrate in […]
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Nucleosomes Containing Methylated DNA Stabilize DNA Methyltransferases 3A/3B and Ensure Faithful Epigenetic Inheritance
Read the study published in PLoS Genetics How epigenetic information is propagated during somatic cell divisions is still unclear but is absolutely critical for preserving gene expression patterns and cellular identity. Here we show an unanticipated mechanism for inheritance of DNA methylation patterns where the epigenetic mark not only recruits the catalyzing enzyme but also […]
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Male pattern baldness and the risk of prostate cancer
Annals of Oncology Background: Androgens play a role in the development of both androgenic alopecia, commonly known as male pattern baldness, and prostate cancer. We set out to study if early-onset androgenic alopecia was associated with an increased risk of prostate cancer later in life. Patients and methods: A total of 669 subjects (388 with […]
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BCR–ABL-mediated upregulation of PRAME is responsible for knocking down TRAIL in CML patients
Of Oncogene Tumor necrosis factor-related apoptosis-inducing ligand—TNFSF10 (TRAIL), a member of the TNF-α family and a death receptor ligand, was shown to selectively kill tumor cells. Not surprisingly, TRAIL is downregulated in a variety of tumor cells, including BCR–ABL-positive leukemia. Although we know much about the molecular basis of TRAIL-mediated cell killing, the mechanism responsible […]
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Algae holds promise for nuclear clean-up
By Naturenews Common freshwater algae might hold a key to cleaning up after disasters such as Japan`s Fukushima nuclear accident, scientists said yesterday at a meeting of the American Chemical Society in Anaheim, California. The algae, called Closterium moniliferum, are members of the desmid order, known to microbiologists for their distinctive shapes, said Minna Krejci, […]
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OMS reconhece importância do Laboratório de Modelagem e Biodosimetria Aplicada (Lambda)
Da Agência de Notícias da UFPE Grupo de Estudos em Radioproteção e Radioecologia (Gerar) do Departamento de Energia Nuclear (DEN) da UFPE ganhou reconhecimento internacional. O Laboratório de Modelagem e Biodosimetria Aplicada (Lambda), filiado ao Gerar, passou a integrar o grupo de trabalho Biodosinet da Organização Mundial de Saúde (OMS). O convite decorreu da publicação […]
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Redes Neurais e Bioinformática na Semana da Computação da UFRPE.
Entre os dias 13 e 16 de Outubro, a UFRPE reúne professores, estudantes e interessados em informática, em evento onde serão discutidos Redes Neurais e Bioinformática, entre outros temas. Com inscrições a preços simbólicos (R$ 10,00), a Semana da Computação da UFRPE contará com a participação de vários especialistas brasileiros. Confira os detalhes pelo link: http://secomp.orgfree.com/inscricaocad.php
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Participação da SBBN na Reunião Anual da FeSBE-2010
Com palestras, cursos e apresentação de posters de trabalhos científicos, a SBBN participa como entidade associada à FeSBE – Federação de Sociedades Brasileiras de Biologia Experimental, na sua XXV Reunião Anual, em Águas de Lindóia, São Paulo. Os destaques da participação da SBBN são: Quarta, 25 de agosto – 18h00 – 19h00 – Cursos Imunologia […]